Sentence examples for biological disc from inspiring English sources

Thus the aim of this study was to develop a natural disc scaffold for culturing disc cells for future development of biological disc constructs.

Currently, most findings indicate that PRP could serve as a potential therapeutic candidate to facilitate biological disc repair.

Local injection of a simvastatin-loaded PEG-PLGA-PEG compound was preliminarily found to promote autogenous chondrogenic disc repair and retard disc degeneration, which provides an alternative strategy for biological disc repair in a less expensive and easily applied method.

This clearly stresses the importance of biological approaches to disc repair.

However, the use of rotating disc biological filters for aerobic waste treatment precedes these activities by at least a decade.

In the last several decades, there is a strong need for a tissue engineering strategy that alleviates pain and restores spine function by directly addressing the underlying biological causes of disc degeneration.

Adult mesenchymal stem cell therapy has a potential application in the biological treatment of disc degeneration.

The Noto- cre mouse described here will be a valuable tool for interrogating the function of molecules that regulate the function of notochordal cells within the IVD, with the eventual goal of identifying candidate biological treatments for disc degeneration.

Through identification of important growth factors and transcriptional regulators that are present during the progressive conversion from notochord and sclerotome cells to mature NP and AF cells, respectively, it might be possible to target and modulate specific genes associated with cell survival, differentiation and matrix deposition to advance biological therapies for disc degeneration.

The described notochord-specific Cre mouse model will be a valuable tool in future studies to interrogate the function of candidate regulatory molecules during the processes of IVD development, homeostasis and degeneration, with the eventual goal of identifying candidate biological treatments for disc degeneration.

Engineering strategies that rely upon synthetic materials or composite implants that do not interface with the biological components of the disc have not met with widespread use or desirable outcomes in the treatment of intervertebral disc pathology.