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Although biological differences have been largely attributed to sex hormones [7], the precise nature of the cross-talk between sex and infection remains largely unknown.
Biological differences have been found between primary IBC and other forms of LABC, however, and there is a growing consensus that it is preferable to distinguish between these two forms [ 8, 10, 15- 17].
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Female sex may also constitute a biological diathesis, with sex differences having been shown in a number of biological processes connected with depression [ 49].
Two arguments for the biological basis of this difference have been proposed.
Ethnic differences in vitamin D status have long been recognised [ 27- 30], although the evolutionary factors responsible for the biological differences have not been elucidated.
Methods using less cRNA for hybridization or amplifying the cRNA have been reported to reduce the number of transcripts detected, but the effect on realistic experiments designed to detect biological differences has not been analyzed.
The difference has been growing and observable "for multiple diseases, biological and behavioral risk factors, and injuries".
These differences in biological response have been attributed to differences in the site specific acetylation of p53, stabilized by these two drugs [ 19].
Moreover, differences in biological properties have been demonstrated between sublines of both haematopoietic and breast cell lines (Osborne et al, 1987; Band et al, 1990; Crepin et al, 1990; Lukashov and Goudsmit, 1995).
Differences among fibrous silicates to effect injury in biological systems have been postulated to reflect oxidant generation by structural iron within the crystal lattice of amphiboles.
Other biological controls have been tried.
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