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Koch paces his revelations expertly, and there are twists and turns enough to keep us reading, but his decision to ascribe the former teacher's violent outbreaks to a biological defect – to make Paul's condition something other than simply the human condition – diminishes the book.
Though Asperger regarded it as a biological defect of affective contact innate, inborn, analogous to a physical or intellectual defect Kanner tended to view it as a psychogenic disorder, a reflection of bad parenting, and most especially of a chillingly remote, often professional "refrigerator mother".
Though Asperger regarded it as a biological defect of affective contact — innate, inborn, analogous to a physical or intellectual defect — Kanner tended to view it as a psychogenic disorder, a reflection of bad parenting, and most especially of a chillingly remote, often professional "refrigerator mother".
In acute toxicity study, the B. ceiba extract was found to be safe and did not reveal any biological defect and mortality in rodents.
Mutational patterns, which are probably more closely related to the underlying biological defect, therefore appear to report similarities in disease pathogenesis between BRCA1 and BRCA2 mutant cancers better than cellular phenotype.
For example, retinal cells can be generated in culture from patient-derived iPSCs and used to study whether the introduction of specific genes into these cells can compensate for a biological defect in their function.
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Therefore, the understanding of the in vivo roles of the NMD pathway will require the identification of these targets, particularly those that display increased expression in NMD mutants, as it is likely that this increased expression mediates the biological defects observed in NMD-defective organisms and cells.
The phenotypic and biological defects were rescued by PIG-A transgene expression.
Animal models can be generated to characterise different stages of this complex control process to understand the particular biological defects that can lead to these pathologies.
In the case of people with major biological defects, education is still a way to get over these obstacles and society should be ready to help these people (38 Student).
Psychiatric diagnoses are not genuinely medical; they are not based on biological defects or disorders.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com