The authors also thank S. Consalvi, M. Charpentier, A. Boucharlat and the Chemogenomic and Biological screening core facility at the Institut Pasteur in Paris for support during the course of this work.
In an effort to tease out biological knowledge, core and pan-genome sizes have been determined for numerous species (Huang et al. 2014).
To what extent could we specifically measure whether students are using the asserted core biological concepts to organize their biological knowledge?
To investigate the biological function of core 3-derived O-glycans, we engineered mice lacking core 3 β1,3-N-acetylglucosaminyltransferase (C3GnT), an enzyme predicted to be important in synthesis of core 3-derived O-glycans.
These alignments provide evidence that conserved regions of DIA1 are vital to the core biological function of the protein, and support the notion that this biological role is conserved in all metazoan species with a DIA1 orthologue.
DQCs are sets of interrelated questions about core biological concepts and ideas designed to identify problematic patterns in students' thinking about biological content (D'Avanzo, 2008).
"By showing that three causes of paternal absence decrease telomere length, a core biological indicator of health, the authors are able to provide insight into a direct biological channel through which paternal absence could affect the health of their children," Wildeman added.
