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It's a very complex subject – not least because there may be crossover between the cultural and the biological; between the BPS's dismissal of diagnostic labels and the NIMH's desire to find a biomarker for every illness.
– lTo compare the cumulative incidence of patients with persistent RA flare resulting in change of biological between the intervention and the usual care group after 9 months and after 18 months of follow up.
Comparisons among the 10 μg samples from different animals within each of the treatment groups showed that the biological (between animal) plus random technical variability is considerable (Table 4, 10 vs. 10).
A total of 9139 patients with RA initiating TNFi as their first ever biological between 2003 and 2011 were identified, with 26% starting adalimumab, 43% etanercept and 32% infliximab (table 1).
Different design models in LIMMA allowed a global comparison of the precocious and non-precocious gonads but, in addition, the different pools (i.e. 1 to 3) could be compared to each other: this was of interest as it could highlight any variation (either technical or biological) between individual samples.
Given that the estimated total standard deviation in the GPS (including all pre-analytical, tissue related and biological between patient variability) is approximately 11.4, the analytical assay variability is estimated to account for only 3.4% (= 100 × 2.11 / 11.4) of the total variation.
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However, despite the biological relationship between these two genes, no statistical associations were observed between them.
Schematic diagram of the biological interaction between NPM and protein.
Part of it may be explained by the biological differences between men and women.
There might even be biological differences between optimistic and pessimistic people that give optimists an edge.
But the biological interplay between inactivity and exercise has been puzzling.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com