Many GO Biological Process annotations are assertions based upon mutant phenotypes.
It is also a comparative genomics system that incorporates both calculated and human-curated assertions of biological processes and properties of sequenced genomes.
This highlights the value of mechanistic studies, which in only 5 years have replaced previous assertions of biological implausibility with new evidence that formaldehyde can cause blood-cell abnormalities that are characteristic of leukaemia development".
The Selventa Knowledgebase is comprised of causal and non-causal assertions between biological entities or processes derived from peer-reviewed scientific literature as well as other public and proprietary databases.
For most people, creationism is not a biological explanation, but an assertion that there is something special about humans which sets us apart from all other animals.
First, de novo protein design has complicated the assertion that biological function is equivalent to biological structure — demonstrating the capacity to abstract active sites from natural contexts and paste them into non-native topologies without loss of function.
Accordingly, the selection of the candidate biomarkers was a relatively unbiased process, although we recognize some might consider assertion of biological and mechanistic plausibility and the technical limitation of being able to measure the protein in the serum compartment as causes of bias.
Thus, a big linked biological knowledge graph (also called assertion component (ABOX)) can be created based on the TBOX.
Overall, validation using both internal (leave-one-out analysis) and external (comparison with annotated biological features) measures supports the assertion that our method successfully generates reliable predictions of epistatic relationships of both positive and negative polarity.
Although Crump et al. (2008) noted that they "…have not examined whether the upper end of the range of additional risk is consistent with existing human epidemiology because that is not germane to the point we are making" this assertion makes little biological or practical sense.
