Sentence examples for biological activity of specific from inspiring English sources

Computer assisted prediction of the biological activity of specific chemical compounds considering their chemical structure is now a common technique used in drug discovery [16, 17].

Computational simulations is increasingly facilitating rational design of small molecules that can inhibit or stimulate the biological activity of specific proteins, mostly by targeting a clearly defined binding pocket.

More recent work by Seydel and collaborators has led to the realisation that the biological activity of specific lipid A structures can be determined by an understanding of their supramolecular structure, which is a function of the monomeric conformation, which in turn is largely determined by the primary molecular structure [ 83, 99, 100].

This particular, structurally illogical naming convention goes back to the fundamentally different biological activities of specific compounds with a pregnane or androstane backbone, resulting in the perception that androstanes and pregnanes do not show a parent child relation but are rather sibling concepts at the same hierarchical level.

In phase I, the biological activity of the specific metabolite is reduced, with cytochrome P450s acting as principal enzymes [ 6].

Demonstration of relevant, potential biological activity on specific molecular targets is followed by the identification of putative lead compounds.

The biological activity of CelTOS-specific antibodies against the malaria parasite is likely linked to the impairment of sporozoite motility and hepatocyte infectivity.

To test the biological activity of peptide-specific antibodies, the latter were purified by affinity chromatography using three serum pools obtained from Papua New Guinean adults.

The James Webb Space Telescope will launch in 2018 and has an infrared sensitivity capable of searching for traces of biological activity.

The ensuing analysis of the biological activity of these vanadoforms unravels specific roles for vanadium, commensurate with its physicochemical nature and properties.

Given the structural similarities between p63, p53 and p73 [ 55], their DNA-binding affinity towards similar DNA sequences and the proclivity to heterodimerize, it is likely that the biological activity of p63 in a specific cell type will be greatly influenced by the presence or absence of the other two family members.