Sentence examples for biological activity based on from inspiring English sources
This study proposes the development of new compounds with dual biological activity, based on biologically active components: ethanolammonium as cation and 2-chloro-4-nitrobenzoate, 2-chloro-5-nitrobenzoate and respectively 4-nitrobenzoate as anions.
We present here a neural networks method designed to predict biological activity based on a local representation of the ligand.
We produced the selected chemokines and confirmed their purity as well as their biological activity based on their ability to mobilize intracellular calcium in primary neutrophils (Supplementary Fig. 1a d).
We describe a fast, sensitive, specific, and simple in vitro assay for GH biological activity, based on the differentiation of 3T3-F442A cells into adipocytes.
Molecular similarity relationships are analyzed among compounds with related biological activity based on the evaluation of randomly generated fragment populations.
While some research has focused on predicting biological activity based on these data, the results have not provided insight on characteristic structures [4, 5].
Structural diversity is not the only reason why natural products are of interest to drug developers, since they often provide highly selective and specific biological activities based on mechanisms of action.
In particular, the last decade has witnessed an exponential growth in the generation of novel candidate therapeutics of multiple biological activities based on graphene constructs with small molecules, such as anti-cancer drugs.
Our findings show that signalling pathway activation is cell-specific with dose- and time-dependent profiles making it near impossible to rank biological activities based on such assays.
Using Pharmaexpert (www.genexplain.com/pharmaexpert), a tool developed to analyze the BAS of substances predicted by PASS, we characterized EVOO oleuropeins with different types of biological activities based on multiple mechanisms of action, analyses of activity-activity relationships, and drug-drug interactions.
