Finally, knowledge of CTCL genetics could improve biologic understanding of this group of diseases and facilitate the development of more specific, targeted therapies.
As our biologic understanding of these diseases advances and new targets emerge, therapies will become more enlightened.
Designing rational therapies for treatment will have its foundation in the biologic understanding of involved genes and molecular pathways in these types of tumors.
As these advances in molecular knowledge contribute to the biologic understanding of DLBCL, targeted treatment strategies can be developed and refined.
The current biologic understanding of depression posits that many aspects of depression can be understood in terms of dysregulation of the Central Nervous System CNSS) responses to stress and naturally dysregulation is influenced by a wide range of moderating variables such as genetics, age, sex, and developmental history.
Past classifications of lymphomas do not reflect the current biologic understanding of NHL and do not make distinctions between different cell types.
The characterisation these activation states, of stimulatory and inhibitory interactions and their correlation with the clinical effects of trastuzumab will clearly have a profound effect on our biologic understanding of receptor signalling and ultimately refine targeted therapies.
The failure to know whether treatments that don't work over all might help some patients is not a failure of clinical trials, but rather reflects our limited biologic understanding, the focus of basic research.
Such advances would facilitate a more rapid approach to dissecting the confounding effects of linkage disequilibrium and speed translation of GWAS results into biologic understanding that can be applied to improve the lives of patients with autoimmune diseases.
Future integrated applications with PET-CT findings or dual-energy CT may enable more understanding of the biologic behaviour of the tumour in vivo, making the CTp one of the potential cornerstone of biologic imaging of HNSCC.
