Trace amounts of metals in biologic systems are essential for processes such as respiration, nerve function, and cell metabolism.
Unfortunately for biologic systems, empiric formulation is insufficient to promote adequate integration in a timely fashion.
Some of these compounds, referred to as metal clusters, have characteristics of metals, while others react in ways similar to biologic systems.
The idea of a supernatural "consciousness" directing evolution would find a home among advocates of intelligent design creationism, for whom the "intelligent designer" creates the "information" of biologic systems, with humans occupying a special, privileged status among other animals.
He knows how biologic systems work — and, equally important, he is an expert observer of those who observe for a living, and well acquainted with scientific doublespeak.
The mechanical properties of matrix and basement membranes in biologic systems are difficult to understand in detail because of their complexity and technical limitations of measurements.
Observation of the in vivo vasculature is difficult due to the complexities of vessel geometry, limited visualization capability, as well as variability and complexity inherent to biologic systems.
In improving the success rate of effective drug development, it is equally imperative that biologic systems be developed to better validate these target genes.
In different fields of science and engineering (medicine, economy, oceanographic, biologic systems, etc) the False Nearest Neighbors (FNN) method has a special relevance.
Reduction in integer heart rate variability (HRVi), one potential measurement of complex biologic systems, is common in ICU patients and is strongly associated with hospital mortality.
Traditional approaches to pathophysiology are advancing but still have many limitations that arise from real biologic systems and their associated physiological phenomena being too complicated.
