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Indubitably, full understanding of LN responses following experimental immunization represents an essential step to provide a rationale biologic platform for the development of LN research in humans.
These new anti PrPc human antibodies are unique reagents for prion protein detection and may represent a biologic platform to develop new reagents to treat PrPsc associated disease.
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The type 3 secretion competent E. coli strains described here thus represent a novel and highly promising biologic-based platform for the targeted delivery of defined therapeutic molecules into mammalian cells.
Optical biosensor devices are emerging as powerful biologic agent detection platforms satisfying these considerations.
The main risk factors identified for sustained employability were related to job demands and job design (machine handling, knife handling, repetitive movements, static postures, work pressure), and contextual factors (work on platforms, biologic agents, noise, safety measures) [ 15, 16].
biologic or biological #16.
We sought to determine the practical strengths and weaknesses of four leading commercially available expression array platforms relative to biologic investigations, as well as assess the feasibility of cross-platform data integration for purposes of biochemical pathway analyses.
Cytokine network architecture creates an innate cell-communication platform that organizes the biologic outcome of antigen recognition and inflammation.
Thus, accurately documenting such an advantage is crucial for plant-based systems to be recognized as a serious platform for manufacturing protein biologics.
The experimental program of the HESI Genomics Committee clearly demonstrated that it is possible to replicate data on biologic pathways across laboratories and technical platforms (Kramer et al. 2004; Ulrich et al. 2004).
We conclude that KrasLA1/+; p53R172HΔG mice will provide a useful platform to better understand the basic biologic processes that underlie metastasis, to identify biologic targets for the prevention and treatment of metastasis, and to test the efficacy of novel agents directed against those targets in preclinical studies.
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