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Furthermore, a thorough understanding of the complex biologic pathways involved in SWL-induced renal injury does not exist at present.
Further research is needed in this area to better understand the complex biologic pathways involved in normal growth and to determine which molecular alterations lead to increased degrees of asymmetry in patients.
Genetic association analyses of phenotypic variation in circulating white blood cell (WBC) counts from large samples of otherwise healthy individuals can provide insights into genes and biologic pathways involved in production, differentiation, or clearance of particular WBC lineages (myeloid, lymphoid) and also potentially inform the genetic basis of autoimmune, allergic, and blood diseases.
Our research team has also examined the potential of mathematical modeling to elucidate apparently contradictory and unpredictable behavior emerging from the plethora of interactions among biologic pathways involved in the acute inflammatory response [52] [54].
Two types of analysis were conducted for the microarray analysis: (i) SAM analysis and (ii) targeted analysis of biologic pathways involved in lipid storage and inflammation.
Combination specific PAH therapy in CTD-PAH targets more than one of the multiple biologic pathways involved in disease pathogenesis [ 2].
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Although some moderate variations were detected (for example, for E-alone and breast cancer [ 10]), these tended to provide limited insight into the biologic mechanisms and pathways involved in the observed clinical effects.
The chemical pathways involved in inactivation of biologics include deamidation, oxidation, hydrolysis, racemization, beta elimination, and disulfide exchange.
The management of RA includes the use of biologic and non-biologic disease-modifying antirheumatic drugs (DMARDs) [ 2, 3], which act by directly modifying immunologic pathways involved in the pathogenesis of RA.
The researchers concluded that the neurological pathways involved in pleasure might also be involved in absence of pain.
Scientists have long known that the biochemical pathways involved in disease are complex, with numerous alternate routes.
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