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Principles of tissue engineering are now being applied in the induction and development of microvascular networks as well as vessel conduits, including the in vitro and in vivo biologic modification of synthetic vascular grafts and the generation of tissue-engineered blood vessels.
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The presence of a statistically significant interaction would suggest the presence of an underlying biologic effect modification and provide epidemiologic clues to the etiology and pathogenesis [ 23].
As the consequence of important biologic and social modifications, in the last century new non-infectious epidemic diseases appeared as the most important causes of mortality in worldwide.
Thus, proteins that require such modification for biologic activity should be studied in their myristoylated form.
Effect measure modification and biologic interaction were also extensively evaluated.
Additional and longer-term investigation of the biologic response to thermal modification after cumulative dosages of RFE using in vivo models is needed.
Full-length adiponectin (fAd) requires posttranslational modification for biologic activity (e.g., hydroxylation and glycosylation) and is secreted from adipocytes in three major size classes: trimers (∼90 kDa; the basic unit), low-molecular-weight (LMW) hexamers (∼180 kDa), and high-molecular-weight (HMW) isoforms consisting of 12-mers to 18-mers (which can exceed 400 kDa) [ 26, 27].
Even after 12 years, the legislation would allow a drugmaker to extend market protection for its biologic by making minor modifications — a small tweak that would change its dosing, for example.
Thus, we aimed to examine the effect of basal biologic factors, weight change, and prevention strategies (intensive lifestyle modification [ILS] or metformin) on the incidence of regression from pre-diabetes to NGR.
biologic or biological #16.
(biologic or biological).ti,ab.
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