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Identification and sequence information for many lncRNAs and other novel transcripts opens the possibility to study their transcriptional responses and begin to explore their biologic function in An. gambiae using functional assays such as dsRNA gene silencing.
Because there has been no laboratory evaluation of the biologic function of COX-2.8473 polymorphism, additional studies to examine the functionality of the polymorphism and the potential interactions with various inflammation-related genes are warranted.
All the distinct gene identifications were examined for their known biologic function according to gene ontology convention and grouped in their respective functional category.
However, once the discriminating elements of the molecular signature are identified, biologic function can be inferred by mapping components to known biologic pathways and verifying functionality in follow-up studies.
However, the biologic function of p38γ MAPK in breast cancer has not been well defined.
Criteria for selection of valuable transgenes are discussed, including biologic function and compatibility with market infrastructure.
Since the biologic function of the HLA molecules is presenting endogenous and exogenous antigens, they manifested high structural polymorphism.
PSMA with the biologic function of glutamate carboxipeptidase II (GCPII) is a membrane-bound zinc metalloenzyme and is expressed in various tissues.
Approximately, 1 in 3 patients with severe hemophilia A produce neutralizing antibodies (inhibitors) that block its biologic function in the clotting cascade.
Among the genes upregulated in tumor tissues compared with their nontumor counterparts, we focused on a novel gene, termed WDRPUH, and characterized its biologic function.
Several identified disease-causing genes are highly conserved in both vertebrates and invertebrates, suggesting their fundamental biologic function in axonal maintenance.
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