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The angiogenic potential of endothelial progenitor cells (EPCs) may be limited by the absence of their natural biologic foundation, namely smooth muscle pericytes.
Understanding the mechanism of action of oral anticoagulants provides a biologic foundation for use of PCCs, aPCCs, and rfVIIa in treatment of uncontrolled bleeding.
Despite a wide range of approaches, periodontal therapies are currently unpredictable, few are truly regenerative, and many lack a biologic foundation.
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Dinarello, C. A. Biologic basis for interleukin-1 in disease.
biologic or biological #16.
Designing rational therapies for treatment will have its foundation in the biologic understanding of involved genes and molecular pathways in these types of tumors.
Although treatment may include surgery and radiation therapy for the treatment of locally advanced tumors or isolated metastases, systemic therapies (endocrine, cytotoxic, biologic, and palliative) are the foundation of disease management [ 6, 7].
Current information on AMP structure, expression, and biologic activity has established a firm foundation for further study of the impact that these peptides might have in human disease.
This section builds a firm foundation for the subsequent chapters, intertwining geologic and biologic chapters.
The collection and archiving of biologic samples (e.g., blood, hair, or urine) could serve as a foundation for some but not all exposure-related research.
Tinbergen (1963) provides a more detailed foundation for evolutionary medicine by outlining the four kinds of questions that must be answered to provide a full biologic explanation for any trait: mechanism, development, function, and phylogeny.
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