It has been suggested that human life events can alter stable biological mechanisms and turn them into a genetic legacy process called incorporation of biologic features [ 19].
Rational selection based on particular biologic features would be possible using highly parallel investigations of gene content and gene expression of entire bacterial chromosomes.
This is a research-based study that is looking at the biologic features of breast tissue, lymph node tissue, or blood in order to study breast cancer development growth, and spread.
Age-related changes that could affect the biologic features of mesenchymal stromal cells (MSC), such as a decrease in proliferation and osteoblast differentiation capacity and an increase of senescence markers and apoptosis, have been reported recently.
Although some clinical and biologic features have been found to be associated with a lower probability of response to imatinib, at present no precise markers allowing for the prediction of outcome for individual patients exist.
To compare presentation of Alzheimer disease (AD) at the time of initial evaluation at a university specialty clinic across three ethnoracial groups in order to understand similarities and differences in the demographic, clinical, cognitive, psychiatric, and biologic features.
OBJECTIVES AND METHODS: This report describes technical refinements to the murine model and describes additional biologic features of the immune response to mPF4/heparin.
Studies of MGUS revealed that some samples shared biologic features with RMM, which comprised the basis for a high-risk MGUS signature.
We anticipate that further study and understanding of the clinical and biologic features of BRCA-mutant PAC will aid in the identification of tissue biomarkers indicating defective tumor DNA repair pathways in sporadic PAC.
On the basis of these findings, we conclude that the murine model recapitulated biologic features of the subset of NSCLC adenocarcinoma patients with poor clinical outcomes.
The availability of a primate model that reflects the salient biologic features of HIV-1 transmission among humans will enhance our understanding of lentiviral pathogenesis and facilitate the development of an effective vaccine.
