Sentence examples for biologic effect of the from inspiring English sources
Our assay measures the variations of target gene expression that reflect the biologic effect of the therapeutic agent and the capability of the antibodies, if present, to neutralize the therapeutics.
Thus, the distance between Trp183 and the SE-binding site, the dissimilarity in the biologic effect of the two pathways and their distinct compartmentalization, all suggest that the SE and GABARAP binding sites are neither structurally nor biologically related.
The identification of global demethylation relative to control cells confirms the biologic effect of the decrease in DNMT1.
To what extent the biologic effect of the cytokine in milk is modulated by the presence of soluble receptors and other cytokine antagonist is open to speculation.
This type of interaction suggests that the biologic effect of the drug (e.g. an anti-inflammatory effect) is beneficial in high disease severity and that the same biologic effect is detrimental in low disease severity.
226, 227 Current and future trials evaluating combination therapies with molecularly-targeted drugs and bevacizumab have evolved a template structure in which bevacizumab is administered every 2 weeks in 28-day cycles, and the investigational agent is added to the monthly cycles with the scheduling dependent upon the biologic effect of the agent.
The biologic effect of these resistance determinants is often highly dependent on genetic and organismal context; thus, resistance genes may be latent under certain conditions, only to be activated in others.
These ECM scaffolds are typically prepared from porcine organs such as small intestine or urinary bladder, which are subjected to decellularization and terminal sterilization without significant loss of the biologic effects of the ECM.
Recent evidence indicates that there are other functional variants in COMT that modulate the biologic effects of the Val/Met polymorphism and confound simple Val/Met associations [20], [21].
