Sentence examples for biologic development from inspiring English sources

"We structured the deal with the pre-eminent biologic development company in the world," he said.

2.4 For biologic development, it was noted that accelerated (unfrozen) API stability studies as compared to frozen API are very informative for identifying potential changes to be anticipated; however, it is not necessary for formal stability protocol.

Directly targeting the cytokine is a classic strategy in biologic development based on monoclonal antibodies production.

Some of the principles regard knowledge about biologic development of cancer (principles 4 and 7).> Screening for breast cancer with mammography aims at detecting breast cancer at an early, curable stage.

Historically, biologics development involved identifying efficacious doses administered to patients intravenously or perhaps by a syringe.

In this review, we highlight specific examples that demonstrate the growing influence of biomolecular engineering on the discovery and design of immunotherapeutics, with particular emphasis on three strategies in biologics development: (1) Cytokine engineering, (2) Cytokine-targeted antibody design, and (3) Fine-tuning the disease-targeting mechanisms of antibody drugs.

These data were used to estimate the average pre-tax cost of new drug and biologics development.

These results indicate that the binding sites of the VH domain of durvalumab may serve as hot spots for small inhibitory biologics development.

Notes Palani Palaniappan, vice president of biologics development at Millennium Pharmaceuticals who has dealt with two mergers and acquisitions, that between Takeda and Millennium and that of Takeda and Nycomed: "Work on your basic people skills as this is one of the most important criteria to be a team player a trait that is most prized in biotechnology/pharmaceutical industries".

Risks may change in the long term due to factors such as increased urbanization and effluent-dominated instream flows (Brooks et al. 2006), increased disease pressures, demographic change, population increases, technological developments (e.g., move from small molecules to biologics, development of nanomedicines, improvements in drug delivery), and climate change.

This process is laborious, time-consuming, and typically represents a key rate-limiting step in early biologic drug development.