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Influenza vaccine adjuvants, chemical or biologic compounds added to a vaccine to boost the elicited immunologic response, may help overcome this problem.
It is explicit on the existing knowledge that the genus P. hydropiper is affluent in active biologic compounds.
Consequently, development of pediatric PBPK models for biologic compounds is an area which requires ongoing investigation.
Myometrial activity is inhibited by a variety of biologic compounds including progesterone, nitric oxide, and relaxin.
Models for biologic compounds require additional physiologic information regarding tissue-specific lymph flows and receptor-mediated disposition.
Future studies combining 5-FU with other cytotoxic / biologic compounds should consider the mechanism of the interaction and incorporate that information into the design of the trial.
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Moreover we develop a biologic compound (modulator of β-cleavage of APP, MoBA) that blocks β-cleavage of APP but not β-secretase.
Whatever the exact explanation, our data indicate that DEP quinones affect mitochondrial function independent of other biologic effects these compounds may have.
Extrapolating the data from other registries and compounds (biologics and DMARDs) [ 16, 17] over 5 to 10 years demonstrated that, irrespective of the compound, more than half of RA patients will drop out of therapy.
This suggests that the biologic actions of these compounds may be rather complicated.
Combining endocrine therapy with biologic agents, especially antiproliferative compounds, may lead to more effective treatment in the adjuvant as well as the advanced setting.
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