It is explicit on the existing knowledge that the genus P. hydropiper is affluent in active biologic compounds.
Influenza vaccine adjuvants, chemical or biologic compounds added to a vaccine to boost the elicited immunologic response, may help overcome this problem.
Myometrial activity is inhibited by a variety of biologic compounds including progesterone, nitric oxide, and relaxin.
Consequently, development of pediatric PBPK models for biologic compounds is an area which requires ongoing investigation.
Models for biologic compounds require additional physiologic information regarding tissue-specific lymph flows and receptor-mediated disposition.
Future studies combining 5-FU with other cytotoxic / biologic compounds should consider the mechanism of the interaction and incorporate that information into the design of the trial.
In addition, dietary supplements must not include chemical compounds that have been approved as drugs or licensed as biologics, unless the compound was previously marketed as a dietary supplement or a food.
Whatever the exact explanation, our data indicate that DEP quinones affect mitochondrial function independent of other biologic effects these compounds may have.
We show that, rather than chemical diversity, the biologic diversity of a compound library is an essential requirement for hit identification.
This suggests that the MINC assay does not react entirely unspecifically to any drug-like compound or biologic.
