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Using a bioinformatics procedure based on comparative analysis to finished bacterial genomes we found that the amount of detoxification genes present in marine microorganisms seems surprisingly small.
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To shed light on the early evolutionary events leading to the assembly of the pathway, we investigated the distributions, domain architectures and phylogenies of component enzymes using a bioinformatic procedure based on Hidden Markov Model profiles.
Motivated by these observations we improved and updated the grape gene prediction, integrating the information derived from the considerable amount of newly available data and setting up rigorous bioinformatic procedures based on several filtering steps, to limit the number of artifactual genes.
Here, we focus on the Pf parasite erythrocytic stage, a target of protective antibodies and describe a straightforward, rapid procedure based on bioinformatic analysis of α-helical coiled-coil motifs and peptide synthesis.
All 15788 OGs were used as a seed for the functional annotation process based on the bioinformatics initiative Gene Ontology [ 41].
Finally, an automated bioinformatics pipeline based on our stepwise procedure is currently being developed and will be available to other projects that may benefit from this genotyping approach.
The relationship between the mutations and epitopic functions are investigated with bioinformatics tools, based on their sequence information.
Porcine miRNAs were identified based on bioinformatics and based on comparisons to corresponding human miRNA sequences.
We first use state-of-the-art bioinformatics approaches based on multiple sequence alignment across the whole family of GPCRs.
A sensitivity-enhanced bioinformatics approach based on profile-profile comparisons was initially used [ 29].
Moreover we discuss some bioinformatics tools based on their type, methodology and usage.
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