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Thus, we aimed to (1) investigate whether CHH individuals harbor mutations in members of the so-called "FGF8 synexpression" group and (2) validate the ability of a bioinformatics algorithm on the basis of protein-protein interactome data (interactome-based affiliation scoring [IBAS]) to identify high-quality candidate genes.
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It is worth noting that currently available NC-RNA databases mainly rely on bioinformatics algorithms for the identification of non-coding sequences [ 158].
We processed the sequencing data with the use of a bioinformatics algorithm based on our previously reported strategy (appendix 2 on bmj.com).
They also investigated the subclonal architecture and the evolution of breast cancer by performing whole genome sequencing on 21 breast cancers and developing several bioinformatics algorithms to unravel the life history of these tumors [ 16].
Disease classification based on the sequencing results and z scores was generated automatically by the bioinformatics algorithm.
Validating the bioinformatics algorithm established a strategy to rationally modulate cell fate, and optimize stem cell-derived cardiogenesis.
We have implemented several state-of-the-art bioinformatics algorithms and techniques in the software.
A predictive and unified analysis platform based on integrated bioinformatics algorithms and modeling approaches will be developed to crunch through the voluminous experimental data generated by the team.
Despite the successful cloud-oriented implementations of various bioinformatics tools, significantly fewer studies focused on the porting of complex structural bioinformatics algorithms to distributed computing platforms.
Characteristics of individual proteins, their potential (number of serine and threonine residues), and predicted (based on the bioinformatic algorithm O-GlcNAc-Scan [ 19]) O-GlcNAc modification sites as well as references to experimentally validated O-GlcNAc modification sites of these proteins are listed in Table 1.
Bioinformatic algorithms remain the principal means of predicting targets of specific miRNAs.
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