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We processed the sequencing data with the use of a bioinformatics algorithm based on our previously reported strategy (appendix 2 on bmj.com).
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Bioinformatic analysis was performed using an in-house algorithm based on published tools.
The algorithm based on Eqs.
You need to choose a machine-learning algorithm based on the specific task at hand.
This software is a bioinformatics tool that annotates the variants (SNPs, insertions, deletions, and multiple nucleotide polymorphisms) and calculates the effects they produce on known genes present in the annotation of the reference genome sequence through an algorithm based on interval trees, which is implemented in the Java programming language.
The identification of miRNA target genes is usually performed by bioinformatic prediction algorithms based on (i) sequence similarity search, possibly considering target site evolutionary conservation, and (ii) thermodynamic stability.
Because IPA and Onto-Tools Pathway-Express have applied distinct statistical algorithms based on independent knowledge databases, these two bioinformatics tools are complementary, and thus their results are combined.
There are many ICA algorithms based on different independence criteria.
Bioinformatics methods based on the selenoprotein gene assembly algorithm SelGenAmic were used to identify 178 selenoprotein genes from 6 representative species from specific stages of invertebrate evolution.
More recently, two independent large-scale bioinformatic analysis, based on different algorithms of target prediction, claimed that the occurency of intronic miRNA-mediated self-loops (iMSLs) in the human regulatory network is significantly higher than expected by chance [ 10, 26].
The relationship between the mutations and epitopic functions are investigated with bioinformatics tools, based on their sequence information.
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