Sentence examples for bioequivalence concept from inspiring English sources
In fact, the importance of the individual bioequivalence concept is recently being claimed, which would allow the scaling of the established intervals based on the individual comparison and the subject – formulation interaction [ 17, 18].
Based on the bioequivalence concept to achieve similar blood concentrations in all patients, it is possible to calculate preliminary doses that take genotype-dependent differences in bioavailability and drug clearance into consideration [ 77].
These recommendations follow bioequivalence concepts generally accepted by regulatory authorities – that is if two brands of a drug result in blood concentrations which do not significantly differ, the two brands can be considered to be equivalent.
Bioequivalence is a common concept in the field of clinical medicine.
In general, pharmacists seemed to have better knowledge of the concept of bioequivalence and generic drug aspects than physicians.
In general, pharmacists appeared to have a better knowledge on the concept of bioequivalence than physicians, particularly in the case of elderly doctors, in whom the lack of familiarity with the importance of bioequivalence for drug interchangeability was obvious [ 16, 22, 24, 25].
The concepts of bioequivalence and interchangeability are of particular importance in these definitions.
The aim of this study is to provide a quantitative picture of the switchability problem between two generics and to introduce the concept of conditional probability of bioequivalence (BE) acceptance.
"We believe the study and the resulting data will provide further scientific support for the product's bioequivalence to the innovator drug," she said.
