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The first HA developed as a dermal filler was in 1989 by Balazs (Balazs and Denlinger 1989), who understood the biocompatibility of this class of compounds and lack of immunogenicity.
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Further investigation of the bioactivity and biocompatibility of this new class of biomaterials is being performed.
The ocular biocompatibility of this material was investigated.
However, the biocompatibility of this material is not known.
Consequently, it is important that further studies are undertaken on the biocompatibility of this material and its antibacterial effect.
The biocompatibility of this material was recently proven in in vitro and in vivo studies [ 3, 4].
Despite the therapeutic benefits of silicone lenses for PED and LSCD, further research is needed to improve the biocompatibility of this biomaterial.
So far, no direct comparison of read-through efficiency and biocompatibility of the two classes of TRIDs exist.
Apart from these qualities, the biocompatibility offered by the hydrogels has added extra advantage to this class of biomaterials.
Taken together, this class of heparin-based conducting hydrogels showed a promising cross-section of biocompatibility and physical properties for electrode materials as long-term in vitro tissue sensing and stimulation platforms.
Finally, the cell-signaling and biocompatibility properties of this innovative hydrogel are demonstrated, revealing its wide range of therapeutic applications.
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