Sentence examples for biochemical rationale from inspiring English sources

Conclusions: These results call into question the importance of oxidative stress in the disease and the biochemical rationale for clinical trials of antioxidants to prevent and treat preeclampsia.

All corrections apply to the section entitled, 'Biochemical rationale; Eicosanoids: cyclo-oxygenase pathway'.

Here, we present a biochemical rationale for how the proteins encoded by this operon might inactivate digoxin through substrate promiscuity.

Remarkably, a clear biochemical rationale behind the reported effects of glucosamine and CS is lacking in the literature.

New examples of crosstalk continue to redefine the epigenetic landscape, but in most cases, these examples do not include a biochemical rationale.

Our results thus provide a biochemical rationale to the conceptual mechanism of G5 loop movement being the driving factor for GDP release.

CDS is effective in reversing and preventing AMPH-induced behavioral and biochemical alterations, providing a rationale for the design of clinical trials investigating CDS׳s possible therapeutic effects.

The model and biochemical data provide a rationale for Atg7 dimerization: Atg8 is transferred in trans from the catalytic cysteine of one Atg7 protomer to Atg3 bound to the N-terminal domain of the opposite Atg7 protomer within the homodimer.

Alternatively, in silico approaches in which compounds are docked to the structures of predicted targets have also been used in lieu of biochemical screening to generate rationale drug discovery leads.

These compounds were identified with receptor-based virtual screening and then chemically optimized on the base of rationale derived from biochemical screening and molecular modeling.

It is of interest as it presents a detailed molecular rationale for the biochemical function of actin in a non-cytoskeletal regulatory complex, adding to a number of recent structures in which G-actin plays a role as a regulator rather than regulate.