Sentence examples for biochemical pathways that regulate from inspiring English sources

The research of Dr. Lewis Cantley, newly appointed Director of the Cancer Center of Weill Cornell Medical College and NewYork-Presbyterian Hospisal, is focused on understanding the biochemical pathways that regulate normal mammalian cell growth and the defects that cause cell transformation.

Patterns are already beginning to emerge, showing abnormalities in common biochemical pathways that regulate functions such as synaptic plasticity and immune function, said Eric Lander, president of the Broad Institute, in a press conference this morning.

Fusions may drive oncogenic growth by joining a proliferation-inducing gene to an active promoter, by disrupting the function of tumor suppressor genes, or by creating novel functional products that rewire the biochemical pathways that regulate cellular division [ 1].

Both direct stimulation of the specific receptors by growth factors stored in ECM and indirect activation by specific integrin expression and clustering can transmit extracellular biochemical inputs along the intracellular signaling pathways that regulate cell proliferation, survival, and migration [ 24].

Despite the biochemical complexity of plant senescence, significant advances have been made in our understanding of critical components of signaling pathways that regulate leaf senescence.

Guarente, L. & Kenyon, C. Genetic pathways that regulate ageing in model organisms.

However, some of the pathways that regulate these events are poorly understood.

Figure 3: Signalling pathways that regulate human prostatic basal stem/progenitor cell activity.

Other pathways that regulate EMT39 such as Wnt and Notch remained unaffected (Supplementary Fig. 11e, f).

Some biochemical characteristics of aged tissues are con-sequences of their increased pro-oxidant state, and it has been hypothesized that this affects the activities of key signal transduction pathways that regulate these characteristics [ 7- 10].

Although the genetic and biochemical signaling pathways that regulate the conversion from normal developmental patterning to cancer have been intensively studied, an important class of signals remains poorly understood: endogenous bioelectric cues produced by ion channels and transmembrane voltage gradients.