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The approach is illustrated for screening of biochemical paths, a task that involves domains in engineering, agricultural sciences, biochemistry and economics.
Metabolic tinker searches possible biochemical paths between two compounds within this URN using standard search algorithms developed in computer science and graph theory [ 21].
So it is possible that edges may actually have alternative directions, and that is not a strict contradiction of known biochemical paths.
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47 These findings indicated a substantial similarity of chlorophyll breakdown both in senescent leaves and in ripening fruit and suggested that the colour changes observed in ripening fruit and in senescent leaves were accompanied by a remarkably common biochemical path of chlorophyll breakdown.
To sample latent paths in biochemical reaction systems, the RJMCMC method [ 33] first generates an initial reaction path that is consistent with the observations.
Hence, to obtain the knowledge of the rate at which an entire communication takes place depends on detailed model of the molecular dynamics and the biochemical kinetics of every path in the entire communication sequence.
Specifically, the radioactive isotope of phosphorus, P, has been extensively used to trace the path of biochemical reactions.
Models that explore biochemical mechanisms may follow different paths from those mentioned earlier, which addressed the prediction of the activity, not necessarily the mechanism.
The result of this calculation is a table that lists the proteins belonging to the path and the biochemical pathways in which they are involved.
In this article, we sample some of the latest neuroscience research that may lie along the path toward a biochemical "cure" for love, and offer a preliminary ethical framework for dealing with such technology should it happen to arise.
In Arabidopsis, the ATX1 and ATX2 genes have originated from a chromosomal segmental duplication but have evolved divergent biochemical activities as features on the path of neofunctionalization [ 63].
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