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With genetic information and biochemical understanding incorporated, crop modelling also generates new insights and concepts that can in turn be used to improve genetic analysis and biochemical modelling of complex traits.
The accurate calculation of the contributions of electrostatic interactions is very important in biophysical and biochemical modelling as many biological processes are regulated by electrostatic effects.
There are a number of biochemical modelling frameworks which consider both qualitative and quantitative perspectives.
Kinetic biochemical modelling of such reaction circuits (often called biochemical reaction networks) using DEs realizes experiments in silico to enhance our understanding of the complex dynamic systems (Alon, 2006; Chen et al., 2004; Wilkinson, 2006).
The described narrative model of the gp130/JAK/STAT pathway represents an interesting case study showing how, by using this approach, researchers can model biological systems without explicitly dealing with formal notations and mathematical expressions (typically used for biochemical modelling), nevertheless being able to obtain simulation and analysis results.
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von Caemmerer, S. Biochemical Models of Leaf Photosynthesis Vol. 2 (CSIRO Publishing, 2000).
Le Novère, N. et al. Minimum information requested in the annotation of biochemical models (MIRIAM).
Farquhar, G. D., von Caemmerer, S. & Berry, J. A. A biochemical model of photosynthetic CO2 assimilation in leaves of C3 species.
The model comprises over a thousand dendritic spines, where the electrical model interacts with the respective instances of a biochemical model.
As a biochemical model, Manduca sexta has substantially contributed to our knowledge on insect innate immunity.
In particular, we emphasize biochemical models of RL, and point out the future directions.
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