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Critical among them are the biochemical, mechanical and architectural properties of the extracellular matrix (ECM).
"Bioprocessing needs engineers of various kinds [including chemical, biochemical, mechanical, process control, and instrumentation engineers], chemists, and life scientists," he says.
Poor graft survival is often attributed to adverse biochemical, mechanical, and/or immunological stress that cells experience during and after implantation.
The design of biomimetic scaffolds that reproduce the biochemical, mechanical and structural functions of the ECM is a fundamental requirement to develop functional substrate for tissue engineering.
Our objective was to investigate the hypothesis that tissue-engineered cartilage with promising biochemical, mechanical properties can be formed by loading mechanical stress under existing cell cell interactions analogous to those that occur in condensation during embryonic development.
Traditional synthetic substrates and matrices for cell culture have proven to be of only limited utility in efforts to understand and control cell behavior, in large part because they fail to capture the multifarious biochemical, mechanical, geometric and dynamic characteristics of in vivo environments.
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The structure provides new insights into the biochemical and mechanical mechanisms of the mitotic motor domain.
Adhesions can be disassembled through biochemical and mechanical mechanisms [23].
This advanced 2D culture system facilitates investigating the biochemical and mechanical mechanisms of wound epithelium formation during early regeneration in axolotls.
For tissue-engineered cartilage formation with arbitrary shapes, biochemical and mechanical properties, loading dedifferentiated chondrocytes with mechanical stress under existing cell cell interactions has prominent effects.
The primary root attachments possess complex structural, biochemical, and mechanical properties, and their integrity is vital for proper joint mechanics.
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