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Our findings demonstrate that, in as little as 8 weeks, baboons exposed to a high sugar high fat diet gained fat mass and manifested biochemical alterations consistent with the early stages of metabolic dysregulation.
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Further analyses showed that this cell line exhibit phenotypic and molecular alterations consistent with EMT.
These data indicate that p53 knockdown leads to functional alterations consistent with p53 deficiency.
Hand, wrist and knee radiographs demonstrated alterations consistent with osteoarthritis without joint erosions.
Obesity can affect the placenta, resulting in structural and biochemical alterations [ 25– 28], with potential consequent maternal AT growth.
We also analyzed the V162M mutant to determine whether there are consistent biochemical alterations among different disease-causing Rab7 mutants.
While the high-temperature thermal ablation results in acute cell necrosis, hyperthermia (40 46 °C) can induce cellular biochemical alterations that can synergize with radiation (Roti Roti 2008).
Histologically, slight pathological alterations were found in the liver that were consistent with the observed biochemical alterations.
Diabetes mellitus is characterized by hyperglycaemia together with biochemical alterations of glucose and lipid peroxidation [ 6].
The main features of skeletal muscle atrophy, which were highlighted by immunohistochemical and electron microscopy analyses, correlated with biochemical alterations.
23 Activation of these proteases is sufficient to effect morphological and biochemical changes consistent with apoptosis.
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