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Our results further document the presence of a biochemical alteration in GM1 mouse myelin, and suggest that AAV-treatment partially corrects it (Table 1).
Furthermore, the biochemical alteration in lipogenesis in cells with chemical blockade of SCD appears to be located downstream the formation of acetylCoA since a reduced formation of [14C]acetate-labeled lipids was observed in CVT-treated H1299 cells with respect to vehicle-treated controls (Figure 4F).
Together with this biochemical alteration we document increased levels of vascularity within the thyroid.
The permanent weakness motivated a biopsy of the biceps brachii muscle at age 60, revealing myopathy without biochemical alteration.
This biochemical alteration of the apo A-1 lipoprotein could disable the process of reverse cholesterol transport and aggravate an underlying isolated low HDL-C level.
The selected dose of DM was based on previous studies in which 1/10 LD50 induced biochemical alteration in rat without morbidity [ 20].
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This is particularly true for biochemical alterations arising from altered cerebral metabolism and oxidative stress that rapidly occur following the onset of ischemia within the brain.
We also focused on revealing the biochemical alterations that appeared.
The combination also demonstrated an essential reversal of biochemical alterations.
At present, despite the observation of biochemical alterations, specific diagnostic markers are lacking for this disorder.
These biochemical alterations became more intense as QDs liver accumulation gradually increased.
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