Sentence examples for bioavailability of the molecule from inspiring English sources

To our knowledge, the mg/IU ratio for tocofersolan is based on a calculation of the tocopherol content of the molecule and not the bioavailability of the molecule.

These observations indicated that not only the length but also the chemical structure of the alkyl substituent (for example branched alkyl groups) influenced the bioavailability of the molecule.

A 14C-radiolabelled acetyl group was grafted onto the third function and the bioavailability of this molecule was specified in mice after IV administration.

For the same reason, quercetin was entrapped in the polymeric micelle hydrophobic cores [39], and the nanoencapsulation of quercetin in PMs may improve the bioavailability of this molecule significantly.

One of the most popular approaches to improve the oral bioavailability of these molecules is the utilization of a lipid based drug delivery system.

In doing so, care must be taken to retain the non-toxic and oral bioavailability properties of the molecule.

However, the best reported response was stable disease, potentially due to the scarce bioavailability of this molecule [86], [87].

Due to the relatively low bioavailability of the ALA molecule, ester derivatives with different lengths of the aliphatic side chains were designed.

Moreover, murine liver microsomal assay and pharmacokinetics profile (mice, iv, p.o., ip) indicate that the liver is the primary site of biotransformation of the compound, suggesting that both 22a and its metabolite(s) are active, compensating probably low bioavailability of the parent molecule.

By increasing the oral bioavailability of the parent molecule cidofovir, its corresponding prodrugs exhibit increased in vitro antiviral activity against poxviruses, CMV, and other herpes viruses.

The inability to translate the findings from the animal models of PD to clinical benefit may be attributed to several factors, such as the bioavailability of the reducing molecules in the human brain and the effective targeting of mitochondria.