Sentence examples for bioavailability of factors from inspiring English sources

Matrix metalloproteinases also increase the bioavailability of factors, such as bFGF that are essential for the ECM (Haro et al, 2000).

This shedding controls also bioavailability of factors belonging to the TGFα family and, thus, this process is of pivotal importance for liver pathophysiology as many signaling mediators such as TNFα, TGFα, and others [ 21, 22] need to be released from the cell membrane to be active as ligands [ 15, 27, 42].

The action of heparanase is involved in multiple regulatory events related, among other effects, to augmented bioavailability of growth factors and cytokines.

This carrier system is ideal for sustained delivery and enhanced bioavailability of growth factors to the injury or defect site.

Previous studies on Crim1 in various organisms have suggested that it might regulate the bioavailability of growth factors and morphogens.

Functional loss of the fibrils causes epidermal separation, destabilizes the tissue architecture in the papillary dermis and, as a consequence, alters bioavailability of growth factors after tissue damage.

MMP7 is thought to play a role in chondrogenesis by controlling the bioavailability of chondrogenic factors and facilitating collagen type II maturation [20].

Furthermore, MMPs can modulate cell adhesion and proliferation by allowing the bioavailability of growth factors or cell-surface receptors (Fowlkes et al, 1994).

Controlling the bioavailability of these factors or the formation of complexes in which they reside, would directly regulate cytoplasmic control of gene expression in the absence of transcriptional control.

Some probable arguments for these considerations include the limited need of PRP injections in clinics (as PRP is not chronically administered) and the short in vivo half-lives and local bioavailability of growth factors produced by PRP.

Moreover, it is possible to improve controlled and site-specific drug delivery and therefore enhance the bioavailability of growth factors by harnessing the properties of polymer materials, such as biocompatibility and tissue targeting.