Sentence examples for bioavailability of compounds from inspiring English sources

Gastric retention is postulated as an approach to improve bioavailability of compounds with narrow absorption windows.

This review summarizes the discovery and optimization of representative novel oral anticoagulants with the aim to improve selectivity and bioavailability of compounds.

Bioavailability of compounds were checked by in vitro cytotoxicity using CCK-8 celinesnes and confirmed to be nontoxic, but found toxic at higher concentration (50 μM).

Lipinski's rule was originally designed to estimate bioavailability of compounds rather than toxicity.

Particularly, a common trend is low in vivo bioavailability of compounds that exhibit rapid rates of in vitro metabolism [15].

Depending on efflux transporter interference with different compounds, bioavailability of compounds in a mixture can deviate from that of the same components when they are present alone.

The oral bioavailability of compound 115 was ∼10.29% after 30 mg/kg oral dosing assessed in rat.

Third, what may be the optimal dosages, routes of administration, efficacy and bioavailability of compound drugs that raise intracellular NAD+ levels for human application?

The enhanced biodegradation in the micelles solution can be attributable to the increased solubility, dissolution, and bioavailability of compound to bacteria [ 58] and the surfactant enhanced substrate transport through the microbial cell wall [ 59].

The in vitro permeation test (IVPT) has been widely used to characterize the bioavailability (BA) of compounds applied on the skin.

This investigation includes the following main steps: (1) assess the relevance of FFDS and its herbs with pain; (2) drug-likeness and bioavailability analysis of compounds in FFDS; (3) collection of targets for FFDS; and (4) analysis of the potential pharmacological mechanisms of FFDS in the treatment of pain.