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Fluorination is a well-known strategy for improving the bioavailability of bioactive molecules in the lead optimization phase of drug discovery projects.
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Their compositions are reported to be as shown in Tables 1– 3. Bosexil® was formulated according to the Phytosome® delivery system that is aimed at improving the bioavailability and skin affinity of bioactive molecules.
Natural product being reservoirs of various types of bioactive molecules are target of extensive research worldwide.
Marine sponges have been considered a valuable source of bioactive molecules with different pharmacological activities.
ChEMBL is a freely accessible database of bioactive molecules with drug-like properties.
Aspergillus fumigatus has been recognized as a potential source of bioactive molecules (Shukla et al. 2014).
They are key intermediates present in various structures of bioactive molecules.
The extracellular matrix (ECM) is the central element of a pericellular network of bioactive molecules.
Haskap berries (Lonicera caerulea L). are a rich source of bioactive molecules.
On the other hand, coordination of bioactive molecules to metal centres may result greater therapeutic effect.
This biotinylation approach may allow attachment of bioactive molecules that are conjugated to avidin.
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