Sentence examples for bioavailability of active compounds from inspiring English sources

Antiradical compounds were bioavailable in vitro; however, small differences between samples (control and enriched) may indicate higher bioavailability of active compounds derived from the base product (wheat bread) (Table 3).

Figure 2 Chemical structures of active compounds.

(b) The corresponding percentage of active compounds.

Percentage of active compounds in the leaf.

In order to overcome the low solubility and bioavailability of the active compounds, colloidal drug carrier systems such as nanostructured lipid carriers (NLCs) have been developed as drug delivery vehicles [ 10].

Assuming that a relationship exists between plasma concentration of the active moiety and clinical efficacy, knowledge of the bioavailability and disposition kinetics of the active compound would be particularly useful in the development of dosage forms and for comparison of routes of administration/formulations [ 12].

It provides many advantages including capability of increasing the bioavailability of poorly soluble compounds, providing protection for sensitive active compounds, and facilitating controlled release of drugs [ 11, 12].

10 However, the efficiency of an active compound depends largely on its bioavailability – it is vital that it reaches the site of action and be released for a prolonged period of time.

Bioisosterism and scaffold hopping are key concepts in drug design and optimization, and can be defined as replacements of biologically active compound's fragments with other fragments to improve activity, reduce toxicity, change bioavailability or to diversify the scaffold space.

Depending on efflux transporter interference with different compounds, bioavailability of compounds in a mixture can deviate from that of the same components when they are present alone.

However, contrary to antiradical activity, obtained results indicated bioavailability of reductive compounds derived from functional supplement.