Sentence examples for bioavailability compared with the from inspiring English sources

The investigated formulations showed more than three folds of improvement in CPX ocular bioavailability compared with the commercial product.

This new microemulsion formulation of CyA demonstrates reduced intersubject and intrasubject variability in absorption and improved oral bioavailability compared with the oil-based CyA formulation.

Interestingly, the lowest concentration group (loaded with an equivalent amount of PTX) of the PTX-MPEG-PLA NPs observably presented lower cell viability than that of free PTX with the concentration of 2.5 μg/mL (P < 0.05), indicating that the PTX-MPEG-PLA NPs presented a more effective bioavailability compared with the free PTX solution.

Significantly, the oral bioavailability of nanocrystalline formulations with particle size of 280 nm was more than 20 times that of the unmilled formulation, whereas the nanocrystalline formulation with particle size of 750 nm showed only a 2.8 times increase in bioavailability compared with the unmilled formulation.

However, the mechanism by which the VKORC1 AG genotype yields the highest bioavailability compared with the other polymorphisms remains to be elucidated.

A relatively increased exposure of artesunate and dihydroartemisinin during the acute malaria phase on day 1 and 2 (87% increase in oral bioavailability) compared with the convalescence phase (at day 7) and post-partum volunteers could be explained by a reduced first pass effect of artesunate.

Furthermore, an in vivo pharmacokinetic study of the optimized SNEDDS formulation showed a 2.2‐fold increase in relative oral bioavailability compared with that of the suspension.

Finally, it is possible that the further improvement observed with vildagliptin is due to a better bioavailability compared with sitagliptin: although the dosage of the two drugs is equivalent, vildagliptin is administered twice daily, whereas sitagliptin is administered once daily, as reported by EMA advice.

This was increased compared with the PCZ suspension although they all improved the bioavailability compared with pure crystalline PCZ.

Despite similar bioavailability compared with enteric-coated tablets, the extended-release diclofenac sodium tablets are associated with a lower Cmax and delayed tmax [ 66, 85– 87] (Table  2).

The relative bioavailability compared with subcutaneous injection (5 IU/kg) in diabetic rats was 11.3% ± 1.05%.