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The bioactivity of the encapsulated VEGF released from the NPs was examined by determining its capacity to induce proliferation of endothelial cells (HUVEC) (Figure 2).
Results indicated that the bioactivity of the encapsulated VEGF released from the NPs was reserved, and the VEGF-NPs thermo-sensitive gel system can achieve sol-gel transmission successfully at appropriate temperature.
The structural properties, as well as the uniform size and autofluorescence, enabled us to develop oral delivery of insulin which conserved the bioactivity of the encapsulated insulin, achieving bioadhesion of microspheres, increasing the loading ability and optimizing the release profile.
The catalytic bioactivity of the encapsulated enzymes GOx/CAT was well preserved during the nanovesicle preparation.
Decreased overall efficacy at later time intervals may reflect both the decreasing concentration of released IL-1ra with time and potentially decreased bioactivity of the encapsulated protein.
Ethyl acetate, on the other hand, exerts less denaturating effects with a lower incidence on the bioactivity of the encapsulated proteins [ 85].
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Finally, to assess the bioactivity of proteins encapsulated using thiol ene gel systems, TGFβ was studied.
(d) EDS result of the encapsulated particles within the nanotube.
10, 11, 17 At the same time, the encapsulating particles on the liquid surface reduce evaporation of the encapsulated liquids.
The dual MRI images of the drug encapsulated nanoeyes will be used to track the location of the encapsulated drug.
Once the substrate is encapsulated in the chamber, the slow hydrolysis of ATP (half-time ~ 10 s) provides time for correct folding of the encapsulated polypeptide.
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