Polyenes containing disubstituted (Z -alkenes are common in bioactive natural products, such as the anticancer protein phosphatase inhibitors in Scheme 1,[ 4] and the efficient synthesis of these motifs is an important goal.
Over the past several decades, Streptomyces strains have been found to produce a number of important bioactive natural products, such as the anticancer compound daunorubicin from Streptomyces peucetius, the herbicide phosphinothricin from Streptomyces hygroscopicus(4) and Streptomyces viridochromogenes, and the antibacterial daptomycin from Streptomyces roseosporus.
Since then, a number of bioactive glass-based products, such as small solid blocks, fine particles, granules, porous scaffolds and injectable putties, have been implanted in millions of patients primarily to repair bone and dental defects.
The observed decrease in COX-2 mRNA after 16 h of incubation with 20 4 LPC followed by a pronounced increase after 24 h might reflect the action of putative, bioactive 20 4 LPC conversion products, such as oxidized or enzymatically modified LPC, whose bioavailability increases during prolonged incubation.
Efforts have been made to use residues to generate several value-added products, such as bioactive substances, used by food, cosmetic and pharmaceutical industries [ 3, 4].
The concept of excipient emulsions could be used to formulate emulsion-based food products (such as excipient sauces, dressings, dips, creams, or yogurts) specifically designed to increase the bioavailability of bioactive agents in natural foods, such as fruits and vegetables.
Products such as Plumpy'nut.
Products such as scented lotions.
