Are you the kind of monster who would use bio-modification technology to surgically transform a butterfly back into a caterpillar?
While the Bio-NHS modification resulted in a considerable reduction in activity compared to the unmodified protein, Bio-ULS-TRAIL displayed almost similar activity as unmodified TRAIL.
Compared with other relative biosensors requiring modified design, bio-molecular modification or/and sophisticated instruments, this CD-based sensor is very simple, cost-effective and easy detection, suggesting great potential applications for successively monitoring physiological potassium level and the change in biological system.
The low toxicity of some of the ionic liquids [11, 12], reusability, ecofriendly nature of ionic liquids and also their ability to improve the enzyme stability and selectivity are the other advantages of ILs for the bio-catalytic modification of phenolic compounds [13 17].
However, for oil crops there are additional objectives concerning the bio-engineered modification of their fatty acid and protein composition, in order to adapt them to specific food, feed or industrial utilisations.
This gives a hint on how criticality characterization can help in bio-system modifications such as in metabolic engineering.
The alkyne represents a benign tag for bio-orthogonal modifications via the Huisgen Sharpless Meldal click reaction for the incorporation of fluorescent or affinity tags that are required to visualize and identify targets, respectively.
The bio-inspired structural modification mimics tree branch trunk joints by embedding the stiffener flange into skin plies.
In order to overcome some of the limitations of chemical modifications, bio-inspired topographical modification of surfaces has recently emerged as an effective route to minimize friction at micro/nano-scale.
Many researchers have made lots of efforts to develop useful algorithms and software to investigate various biology problems such as protein post-translation modification, bio-molecular function classification, protein subcellular locations and protein-DNA interaction [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26].
Supplementary Figure 11 PUP-ITIL2-dependent cell-surface modification of bio-DE28.
