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A titration of r84 against recombinant human or mouse VEGF demonstrated that r84 binds with equal affinity to both species (Figure 1A).
We believe that ppGpp most likely binds with equal affinity as GDP.
In contrast, angiopoietin-2, which binds with equal affinity, has been described as a Tie-2 antagonist, inhibiting receptor activation in response to angio-poietin-1.
Importantly, this antibody binds with equal affinity to both mouse and human EphA3 and no toxicity in normal tissues was observed.
The function of RBP in the brain is unknown but RBP binds with equal affinity to retinol and RA (Breustedt et al., 2006) and cytoplasmic RBP may buffer retinoids and reduce the amount of RA entering the nucleus.
Although mTNF-α binds with equal affinity to both receptors, sTNF-α preferentially binds to TNFR1, which has a death-effector domain that induces caspase-8 cleavage and apoptosis [ 16, 17].
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However, this argument presupposed the validity of what the experiment needed to show, that Pho4 bound with equal affinity to naked and nucleosomal UASp2.
There are five DnaA-binding sites in the oriC region of E. coli, referred to as R boxes, to which both active ATP-DnaA and inactive ADP-DnaA proteins bind with equal affinity [9], [10].
The two ligands share 60% sequence homology and bind with equal affinity to Tie-2.
This calculation assumes that AlkA would bind with equal affinity to all nonspecific sites.
FAM-RNA and RNAs transcribed with T7 RNA polymerase were bound with equal affinity by U1A and U2B″, so the FAM-RNAs were used in fluorescence experiments to measure binding affinity.
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CEO of Professional Science Editing for Scientists @ prosciediting.com