Sentence examples for binds with a high from inspiring English sources

The binding studies show that the CTD of primase binds with a high affinity to the full length helicase and NTDL; poorly with NTD of HpDnaB alone.

LMO4 binds with a high affinity to the LIM domain-binding proteins, LDB1 (CLIM2, NLI1) and LDB2 (CLIM1) (Agulnick et al, 1996; Jurata et al, 1996; Sugihara et al, 1998).

A joint starting point of many drug design approaches is an exhausting search for a drug-like molecule that binds with a high affinity to a desired biological target.

Leu3p binds with a high affinity (Kd = 3 nM) [16] to upstream promoter elements (UASLEU) with a consensus everted repeat sequence 5'-GCCGGNNCCGGC-3' [16] present in a number of genes involved in branched amino-acid biosynthesis in yeast [18], [21].

Interestingly, the insect cuticle-hardening hormone Bursicon consists two proteins, encoded by the genes burs and pburs (partner of burs), and the pburs/burs heterodimer binds with a high affinity to Drosophila LGR2 [31], the fly ortholog of vertebrate LGR4, LGR5, and LGR6.

Annexin A5 binds with a high affinity to these residues.

But VEGF binds with a higher affinity to VEGFR1, which is present on endothelial cells but also on inflammatory cells in tumors or even on the malignant cells in certain tumors [1].

It binds with a higher affinity and has a longer intravitreal half-life than ranibizumab and bevacizumab.

Estradiol binds with a higher affinity to ER than its metabolic products such as estrone and estriol [ 13].

An NMR titration shows that G3P binds with a higher affinity to wild-type cTIM than to the L6RM.

The binding isotherms for JP21 452 and JP2 presented in Figure 4(B) show that the full-length protein binds with a higher affinity than the truncate.