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Exact(15)
Only a certain region of the enzyme, called the active site, binds to the substrate.
Positive ions (SiCH3+) suggest methylene blue binds to the substrate via its methyl groups.
The mechanism involves the homolytic reduction of the diazoate to give a radical that binds to the substrate.
Knowledge of the method in which the metal binds to the substrate can also play an important role in drug design.
The graphene film is separated from the bulk by a carbon-rich interface layer (hereafter called the buffer layer) which in part covalently binds to the substrate.
The Tim8 Tim13 complex assembles as a hexamer and binds to the substrate Tim23 to chaperone the hydrophobic Tim23 across the aqueous intermembrane space.
Similar(45)
The other, protein kinase inhibitor, binds to the substrate-binding site.
The ubiquinone reductase activity was completely stopped by LFN, which binds to the substrate-binding site of DHODH (results not shown).
The triazole derivatives bind to the cytochrome P-450 component of the aromatase enzyme, whereas the steroidal compound exemestane binds to the substrate-binding pocket of the aromatase enzyme (Geisler et al, 1998), leading to its degradation.
BIX-01294 has previously been shown, both structurally and biochemically, to bind to the substrate (histone -binding pocket of Ehistone -binding
Interestingly, both of these inhibitors bind to the substrate arginine-binding cavity of PRMT4 and require the presence of bound cofactor SAH.
More suggestions(17)
binds to the carrier
interconnects to the substrate
binding to the substrate
binds to the putative
binds to the same
binds to the cytoplasmic
binds to the inner
binds to the amino
binds to the mitochondrial
binds to the antioxidant
binds to the central
binds to the upstream
binds to the small
binds to the transcriptional
binds to the specific
binds to the outer
binds to the ribosome
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com