Sentence examples for binds to the signal from inspiring English sources
CD47, also known as integrin-associated protein, binds to the signal regulatory protein alpha on macrophages and inhibits phagocytosis.
The new high-resolution structures also reveal that the hitherto unresolved portion of the SRP subunit that binds to the signal peptide contains two additional helices.
The second path is similar to the bacterial Sec system, where cpSecA binds to the signal sequence in the stroma and guides it through the cpSecYE channel [ 80].
The 54 kDa subunit of the signal recognition particle (SRP54) binds to the signal sequences of nascent secretory and membrane proteins and it contributes to the targeting of these precursors to the membrane of the endoplasmic reticulum (ER).
It is essential for the assembly of molybdenum-dependent DMSO reductase and selenate reductase enzymes in E. coli and binds to the signal peptides of those enzymes with apparent Kd values in the range 10 100 nM [ 43– 43].
This finding sheds light on how the part of the SRP that binds to the signal peptide remains protected from the aqueous cytosol, which was unclear from previous structural studies (Keenan et al., 1998; Halic et al., 2004).
In our model we assumed that FRS2 directly binds to the signaling unit which is distinct from a model described previously [ 25]. pFRS2 subsequently activates the Ras-Raf signaling cascade.
We conclude that the binding of SRP54G domain-specific autoantibodies inhibits the ability of SRP to bind to the signal sequence of PPL.
Thus, DnaK can directly and strongly bind to the signal peptide of CsgA.
In addition, DnaK did not bind to the signal peptides of CsgE, CsgF, or CsgG (Fig. 7d).
These results indicate that DnaK can bind to the signal peptides of some proteins and may regulate the folding status and transport competence of CsgB, a minor component of curli, in addition to CsgA.
