Sentence examples for binds to the shared from inspiring English sources

Ustekinumab, a monoclonal antibody that binds to the shared p40 subunit encoded by IL12B, has undergone phase 2b induction and maintenance trials in patients with CD.

For example, the UGT1A gene family was regulated by miR-491-3p miR-491-3p miR-491-3phared UGT1A 3′-UTR common to all UGT1A enzymes.

Ustekinumab (CNTO 1275, Centocor Inc ,Malvern, PA, USA) is a human monoclonal antibody that binds to the shared p40 protein subunit of human interleukins 12 and 23 with high affinity and specificity, thereby preventing interaction with their surface IL-12Rβ1 receptor.

Unlike other biologics, such as alefacept that target memory-effector T lymphocytes, or TNF-α inhibitors, such as adalimumab, etanercept, and infliximab, ustekinumab is a human monoclonal antibody that binds to the shared p40 protein subunit of IL-12 and IL-23, preventing binding to their receptors and subsequent inhibition of downstream signaling (Table 1).

60– 62 Ustekinumab (CNTO 1275, Centocor Inc ,Malvern, PA, USA) is a human monoclonal antibody that binds to the shared p40 protein subunit of human IL-12 and IL-23 with high affinity and specificity, thereby preventing interaction with their surface IL-12Rβ1 receptor.

Our framework also provides us a non-parametric upper bound to the share of non-manipulators, which we use to characterize the correlates of business tax compliance.

One agent, ustekinumab (Stelara, Janssen Biotech Inc, Horsham, Pennsylvania, USA), is a human immunoglobulin G1 κ monoclonal antibody that binds to the common p40-subunit shared by IL-12 and IL-23.

9 Ustekinumab (Stelara; Janssen Biotech, Inc.; Horsham, Pennsylvania, USA), a human immunoglobulin G1κ mAb that binds to the common p40 subunit shared by IL-12 and IL-23, was approved for treatment of moderate-to-severe psoriasis based upon large phase 3 trials.

RA binds to the RAR receptor, which shares its heterodimerization partner RXR with several other nuclear receptors including TR (reviewed by Rowe 1997).

The crossroads location brings new attention to the shared interests that bind town and gown.

SF-1 binds to shared promoter elements upstream of the steroid hydroxylases to mediate their coordinate expression in steroidogenic cells.