Sentence examples for binds to the response from inspiring English sources

Further ChIP anaylsis showed that indeed in ER+ MCF-7 cells, E2F2 binds to the response element of CDC25A, and this binding is disrupted following treatment with the LXR ligand GW3965.

PXR dimerizes with RXRα and binds to the response elements of its target genes, including CYP3A4 [ 67].

Upon activation with specific agonist, CAR translocates into the nucleus and binds to the response elements as monomers or CAR/RXR heterodimers (Baes et al, 1994).

It has been found that FXR binds to the response elements and induces expression of ADH1A and ADH1B, resulting in increased ADH1 enzymatic activity.

In the 20E signaling pathway, ecdysone receptor (EcR) binds with ultraspiracle (USP) to form a heterodimer, which binds to the response element of early response genes, such as Broad complex (BR-C), E74 and E75 [ 12], to initiate the expression.

SF1 is believed to bind to the response elements of target genes as a monomer.

These kinases phosphorylate and thus activate the critical transcription factors IRF-3 and IRF-7 respectively, which bind to the response elements, eventually promoting expression of types I and III IFNs׳ genes.

The EcR and USP heterodimer binds to the hormone response elements present in the promoters of ecdysone response genes and regulate their transcription [ 4, 5].

The Nrf2/small Maf heterodimer binds to the antioxidant response element (ARE), also known as the electrophile response element (EpRE), the upstream regulatory sequence found in the promoter of cytoprotective genes.

AP-1 binds to the TPA response element (TRE, also known as the AP-1 site) and regulates target gene expression in response to various pro-oxidants and toxicants.

In response to diverse HO-1 inducers, Nrf2 translocates from the cytosol to the nucleus where it binds to the antioxidant response element in the promoter region of the HO-1 gene [ 41].