Sentence examples for binds to the human from inspiring English sources

As shown in Figure 6B, DOSS binds to the human PPARγ ligand-binding domain with a KD of 1,380 nM.

Eculizumab is a recombinant humanized monoclonal IgG2/4k antibody that binds to the human C5 complement protein, inhibiting its cleavage to C5a and C5b and preventing the generation of the terminal complement complex C5b-9 [ 2, 3].

Trastuzumab is a humanized monoclonal antibody that selectively binds to the human EGFR (HER -2 protein, indicated for tHER -2atment of metastatic breast cancers with over exproteinn of HER-2 proteindicated

Although recent studies indicate that UCN-01 binds to the human serum protein alpha1-acid glycoprotein and that this binding may hamper the ability of UCN-01 to inhibit cell proliferation and kill cells in vivo, UCN-01 has decent activity against several tumours at dose levels that are tolerated in clinical studies [ 27, 28].

By using EMSA and ChIP techniques we show that Kaiso binds to the human ICR1.

The receptor binding domain of the spike protein of SARS-CoV/MERS-CoV is a promising antigen candidate since it binds to the human host-cell receptor, angiotensin-converting enzyme 2/dipeptidyl peptidase 4 (Li et al., 2003; Wong et al., 2004; Graham et al., 2013; Lu et al., 2013; Zhang et al., 2014).

The mode of interaction of this series with PPARγ was corroborated through the X-ray crystal structure of 12b bound to the human PPARγ ligand binding domain.

In its crystal structure, (PDB code: 3GID), where Sarophen A is bound to the human ACC 2, the binding site residues are given as Lys274-Ser278-Arg277-Glu593-Met594-Asn599-Asn679-Trp681-Phe704-Trp706. functiona shofs total coresidueon, CT as a functindexf residue index and the residues between Phe704 Ser715, exhibit non-zero values of CT, obtained by using 3GLK.pdb.

However, both TPP and ITP (which contains 40% TPP) bound to the human PPARγ LBD, interacted with binding hot spots within the LBD, activated PPARγ1 transcriptional activity, and stimulated adipogenesis.

AbD15179 clearly bound to the human CD44v6 peptide, whereas no signal was detected for mouse CD44v6.

To determine if Raman microspectroscopy (RMS) can distinguish sperm bound to the human zona pellucida (ZP) from those unbound sperm.