Sentence examples for binds to the enzyme from inspiring English sources

Mixed inhibition is a mode of enzyme inhibition whereby the inhibitor binds to the enzyme irrespective of whether the enzyme is already bound to the substrate or not, but it has a greater affinity for one state or the other.

20, 21 In the crystallographic structure of NDM-1 in complex with L-captopril, the compound binds to the enzyme and its thiol group interacts with the two Zn2+ ions at the catalytic site.

The structural analysis also demonstrates a rotation of the substrate-binding domain when the substrate analogue binds to the enzyme.

Enzyme activity is often modulated by an allosteric effector, a small natural compound that binds to the enzyme at a site distinct from the substrate-binding site.

Substrate binding to active DM-PaDDAH was accompanied by conversion to l-citrulline, which binds to the enzyme with relatively weak affinity, KD DM/ l -cit) = 3.6 mM as measured by NMR.

Noncompetitive inhibition occurs when an inhibitor binds to the enzyme at a location other than the active site.

By definition, an uncompetitive inhibitor binds to the enzyme-substrate complex and hence would be likely to bind close to the active site of the enzyme.

Likewise, a partial non-competitive inhibitor binds to the enzyme-substrate complex but it is assumed that the inhibitor is released from the enzyme at the same time [ES] is broken down to the product [ 73].

Although very flexible, in the wild-type InhA-NADH complex, the NADH molecule keeps its extended conformation firmly bound to the enzyme's binding site.

Moreover, the form of NAD bound to the enzyme determines binding of adenosine, the substrate for the synthetic reaction and the inhibitor of the hydrolytic reaction.

Structurally similar ligands 1 and 2 show almost the same inhibitory activities against VEGFR-2, but they bind to the enzyme in distinct binding mode.