Sentence examples for binds to the consensus from inspiring English sources
For example, the homeoprotein CRX (cone rod homeobox), which itself is expressed predominantly in photoreceptors, binds to the consensus sequence C/TTAATCC/A and has functionally important binding sites present in the upstream region of many photoreceptor-specific genes, including rhodopsin, arrestin, IRBP, and β-phosphodiesterase-6 [19], [24], [24].
Hap4p is a DNA-binding protein that is part of a multimeric HAP complex I that binds to the consensus 5′-TNATTGGT-3′ sequence in the promoter of target genes [ 29, 30] and affects gene expression.
Analysis of the POP-1 binding sites in WBA target genes shows that the C. elegans TCF protein binds to the consensus CTTTGWW site, but unlike TCFs in other species, POP-1 also binds DNA sites with a T in the first position (Jackson and Eisenmann 2012).
The Gal4 protein binds to the consensus Upstream Activation Sequences (UAS) via its DBD and activates transcription of downstream genes through its TAD.
To test whether nvp63 binds to the consensus p53 RE, full length nvp63 protein with a C-terminal myc tag was over-expressed in the human cell line SAOS-2.
Hoxc8, a repressor in the BMP pathway binds to the consensus site of the Opn gene and silences its transcription.
To assess whether the EMT-inducing transcription factors can directly bind to the consensus binding elements present in the promoters of ABC transporters, we undertook a chromatin immunoprecipitation (ChIP) assay with MCF7 cells transiently transfected with pCDNA3-Flag-Twist construct.
Electrophoresis mobility shift assay (EMSA) further demonstrated that AnCrpA could bind to the consensus CRP binding site in E. coli [ 27].
Under certain conditions, NF-κB can also bind to the consensus sequence of the Sp1 binding site, thereby competing with Sp1 [61], [61].
Ac-DAF-16 was previously shown to bind to the consensus DBE sequence and initiate reporter gene transcription [17].
In summary, nvp63 bound to the consensus DNA sequence recognized by hup53 and transactivated target gene transcription in vitro.
